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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRAS All Species: 18.18
Human Site: T84 Identified Species: 30.77
UniProt: P10301 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10301 NP_006261.1 218 23480 T84 A R L D I L D T A G Q E E F G
Chimpanzee Pan troglodytes XP_524339 218 23448 T84 A R L D I L D T A G Q E E F G
Rhesus Macaque Macaca mulatta XP_001115362 218 23436 T84 A R L D I L D T A G Q E E F G
Dog Lupus familis XP_533617 218 23548 T84 A R L D I L D T A G Q E E F G
Cat Felis silvestris
Mouse Mus musculus P10833 218 23745 T84 A R L D I L D T A G Q E E F G
Rat Rattus norvegicus P97538 208 23869 G85 R E Q Y M R T G D G F L I V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519605 176 20687 V67 G F L L V F S V T D R G S F E
Chicken Gallus gallus P08642 189 21347 C80 R T G E G F L C V F A I N N T
Frog Xenopus laevis Q7ZXH7 184 20815 G75 R D L Y M K N G Q G F A L V Y
Zebra Danio Brachydanio rerio Q6TEN1 184 20809 G75 R D L Y M K N G Q G F A L V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P04388 192 22217 L81 M R S G E G F L L V F A L N D
Honey Bee Apis mellifera XP_393035 199 23005 R83 A M R E Q Y M R S G E G F L L
Nematode Worm Caenorhab. elegans NP_496623 212 24407 Q84 E F S T M R E Q Y L R T G S G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P22126 213 24008 R99 R E S F E E I R I Y Q Q Q I L
Conservation
Percent
Protein Identity: 100 99.5 99 97.7 N.A. 94.5 49 N.A. 52.2 48.6 44.9 44.9 N.A. 56.8 56.8 55.5 N.A.
Protein Similarity: 100 99.5 99.5 99.5 N.A. 97.2 60 N.A. 61.9 60 58.2 58.2 N.A. 69.2 69.2 64.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 13.3 0 13.3 13.3 N.A. 6.6 13.3 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 26.6 6.6 26.6 26.6 N.A. 6.6 33.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 51.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 65.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 0 0 0 0 0 0 0 36 0 8 22 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 36 0 0 36 0 8 8 0 0 0 0 8 % D
% Glu: 8 15 0 15 15 8 8 0 0 0 8 36 36 0 8 % E
% Phe: 0 15 0 8 0 15 8 0 0 8 29 0 8 43 0 % F
% Gly: 8 0 8 8 8 8 0 22 0 65 0 15 8 0 43 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 36 0 8 0 8 0 0 8 8 8 0 % I
% Lys: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 58 8 0 36 8 8 8 8 0 8 22 8 15 % L
% Met: 8 8 0 0 29 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 0 0 0 0 8 15 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 0 0 8 15 0 43 8 8 0 0 % Q
% Arg: 36 43 8 0 0 15 0 15 0 0 15 0 0 0 0 % R
% Ser: 0 0 22 0 0 0 8 0 8 0 0 0 8 8 0 % S
% Thr: 0 8 0 8 0 0 8 36 8 0 0 8 0 0 8 % T
% Val: 0 0 0 0 8 0 0 8 8 8 0 0 0 22 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 22 0 8 0 0 8 8 0 0 0 0 22 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _